Fratellone Medical Associates

Plaquex Program

Plaquex® is the treatment of choice for treating coronary artery disease, which is also known as atherosclerosis or the deposit of fatty plaques in the arterial and capillary lining of the blood vessels. Fratellone Medical Associates is pleased to be the first practice in New York City to offer this treatment. Plaquex utilizes a mixture of essential phospholipids derived from soy beans (lecithin phosphatidylcholine), which are delivered in a series of intravenous infusions to clear blocked arteries.


Plaque buildup in the heart
Warning: Individuals who are allergic to soybeans and lecithin should not use Plaquex. Intravenous Plaquex infusions have been shown to be effective in treating the following cardiovascular conditions:

  1. Coronary artery disease
  2. Cardiac trauma such as heart attack (myocardial infarction) and risk of trauma
  3. Angina pectoris

Before the Treatments
Prior to starting Plaquex, all heart patients must have a thorough physical examination. Dr. Fratellone will also discuss your present use of medications such as beta-blockers, nitroglycerin, etc. Additionally, you will undergo one of the following tests:

Finally, your levels of homocysteine, fibrinogen and cholesterol, including HDL and LDL, plus triglycerides, will be tested before and during treatments.

How Plaquex Is Administered
Intravenous infusions typically last from 60 – 90 minutes. Twenty to thirty Plaquex infusions are usually alternated with 10 – 15 conventional chelation treatments. Patients with severe cases of heart disease—by-pass and angioplasty candidates, for example—may require up to 40 treatments of Plaquex alternated with 20 chelation treatments. Patients who have already had chelation therapy need not repeat it before their series of Plaquex infusions.

After the Treatments
Dr. Fratellone will regularly see the patient after treatment. The following will be expected:

Although Plaquex has a lasting effect, should symptoms reoccur, another short series of treatments is definitely recommended. Even without recurrence, it is advisable to undergo a short series once a year. Your long-term prognosis is directly impacted by your overall health and the severity of your diagnosis. Lifestyle choices such as smoking, drinking, eating a healthy diet, exercising and stress levels will also play an important role in determining your results.

The Benefits of Plaquex

Plaquex has been shown to reverse age-related changes in the lipid composition of vital organs and tissues such as heart cells and red blood cells. Clinical studies using Plaquex on laboratory animals have shown an average 36% increase in lifespan.

In addition to clearing blocked arteries, Plaquex increases an individual’s ability to withstand cardiac stress, making it valuable for individuals who have suffered cardiac trauma such as myocardial infarction or who are at high risk of heart trauma.

Because Plaquex has the ability to clean the body’s 75,000 miles of blood vessels, there is also typically a dramatic improvement in cerebral function and a return of sexual potency. Additionally, Plaquex reduces homocysteine levels, thus normalizing levels of HDL/LDL cholesterol and triglycerides and making it unnecessary to continue taking cholesterol-lowering drugs.

Plaquex has also proved useful in the treatment of angina pectoris in patients who also have coronary artery disease. During the course of treatment, the patient may notice a reduction in the symptoms of angina.

The treatment has also shown marked improvement in patients with reduced blood flow to the brain, heart and other vital organs such as the kidneys as well as to the extremities. Since Plaquex treatments improve circulation throughout the body by reducing soft plaque, diseases such as Alzheimer’s, macular degeneration, peripheral vascular disease and liver disease have shown benefits from this program. For more information, visit

Our approach at Fratellone medical treatment center is to provide our patients for extensive ongoing conventional medical care, while providing the most effective integration with alternative treatments.