Until tomorrow…
NOVEMBER 23, 2022 MONOCLONAL ANTIBODIES
From WEB MD
“ Nov. 21, 2022 -- Lab-created monoclonal antibodies, once a leading way of protecting people against COVID-19, are being sidelined because they don’t work against a growing number of coronavirus variants.
"Monoclonals had their day, like the Model T or the biplane," Carl Dieffenbach, director of the Division of AIDS at the National Institutes of Health and lead of the NIH's Antiviral Program for Pandemics, told NPR. "Now it's time to move on."
More than 3.5 million infusions of monoclonal antibodies have been given in the United States since first being authorized in 2020 before COVID vaccines were available, NPR reported.
Monoclonal antibodies are created in a laboratory and work like the natural antibodies your body makes to fight illness. For COVID-19, they’re designed to bind to spike protein on the virus’s surface, stopping the virus from invading human cells.
But the monoclonal antibodies designed for one strain of COVID may not bind to the spike proteins of other strains. Many companies stopped making monoclonal antibodies because they don’t want to spend millions creating a product that will be quickly scrapped, NPR said.
This is a problem for millions of people with weakened immune systems who may not respond well to COVID vaccines, The Washington Post reported. Those people need antibody therapies for protection.
Last January the FDA revised its emergency use authorization for two monoclonal antibody combinations to treat mild-to-moderate COVID-19, because they are not effective against the dominant Omicron variant. The drugs were for bamlanivimab combined with etesevimab from Eli Lilly and casirivimab with imdevimab from Regeneron. “
Most have had COVID or been vaccinated or been vaccinated and had COVID. I feel we should have a good immune system I advocate patients taking daily Vitamin D, methylated B12, zinc, N acetyl cysteine or reduced gluthathione, and liposomal Vitamin C to prevent COVID. If you get COVIUD while on these supplements, the illness will not be as bad. Consult your health care practitioner
Until tomorrow
NOVEMBER 22, 2022 ORAL HEALTH AND HEART DISEASE
Periodontal health has been closely linked to vascular health in many studies. This is NOT a new concept. As early as 2001 in The Annals of Periodontal, Kuramitsu published a study on the Role of periodontal bacteria in cardiovascular disease. In 2011 once again validated this point. Mice were given oral bacteria. Studies found that the oral bacteria affected the gene expression profile of these mice in the aorta and liver and was connected to imbalances of the lipid profile. Low term oral bacteria is associated with a low good cholesterol (HDL) and imbalances in the total and bad lipoproteins. I find it most interesting when I see a low HDL (good cholesterol). I always look at the triglyceride levels because high triglycerides means a low HDL (this could be metabolic syndrome known as Syndrome X). When I see a low HDL and a normal TG, I always ask about the patent's gum health and last dental cleaning. I also ask whether the patient flosses or uses a water pik. I only water[ik. My dental hygienist/herbalist is amazing Her name is Sandra Senzon. She is the tooth fairy She works her magic in decreasing size of pockets and reduces plaque
There are other studies that have shown changes in arterial calcium distribution when these same mice were exposed to oral bacteria. I find this more interesting since I always view CT angiograms and calcium scores. When treating calcium with EDTA suppositories (read the book, The Calcium Bomb), I always add a bedtime oral antibiotic
Studies show that 30% of those with poor periodontal health will develop cardiovascular disease.Retrospective studies reviewing the National Health and Nutrition Examination Survey (NHANES) found that those patients with better periodontal health were more likely to have optimal coronary health.
Even the large meta-analysis done for the last 18 years found that the ability to maintain optimal heart health was found to be higher in subjects whose gums were healthy.
It goes to reason that if oral health is related to cardiovascular health it must also affect the patients blood sugar. This makes sense to me as diabetes and obesity are the twin epidemic leading to this country's number #1 killer: Cardiovascular Disease.
Until tomorrow...
NOVEMBER 21, 2022 THE KINDNESS HORMONE
For the last few weeks on my daily train ride to New York City besides stitching I have been listening to various podcasts. I have been listening to Feel Better Live More with Dr Chatterjee. His British accent brings me back to the days studying medicine in England. Bitesize, his weekly podcast is for your mind body and heart. He features inspirational stories Listen to him
I listened to episode 104 and 105 this morning The first episode featured Dr David Hamilton who has a special interest in the mind body connection He is pharmacist turned author who discussed the kindness hormone, Oytocin . Oxytocin is a hormone that's produced in the hypothalamus and released into the bloodstream by the pituitary gland. Its main function is to facilitate childbirth, which is one of the reasons it is called the "love drug" or "love hormone. Dr Hamilton discussed the research in various settings where oxytocin was measured after acts of kindness. I found this to be exciting and interesting Kindness is good for our happiness and our health.
As a sober individual I try to do acts of kindness in my everyday life. It might be in sharing on Facebook an inspirational quote, or writing a daily blog, or opening a door for anyone and even giving a homeless individual a dollar to get food in this cold weather. Kindness does not hurt
PERFORM AN ACT OF KINDNESS TODAY