Recently in the Cleveland Clinic Journal of Medicine there was an article that peaked my interest It was titled,
What is the role of supplementation with ascorbic acid, zinc, vitamin D, or N-acetylcysteine for prevention or treatment of COVID-19?
The article discussed a brief paragraph on Vitamin C, zinc, Vitamin D and N-acetyl cysteine supplementation. I use each of these supplements in my practice as oral and some as IV. I have utilized intravenous ascorbic acid ( vitamin C) for many years. I have different IV formulations for a number of medical conditions. I also in certain formulas give IV zinc and IV NAC ( the precursor) to glutathione. I do also administer IV glutathione. Vitamin D is a fat soluble vitamins as is Vitamin E, A and K. These cannot be given in an IV form , but can be used as an intramuscular injection. I believe higher doses than the RDA( recommended daily allowance) have been helpful in most of my patients in not getting COVID, and those who had COVID and were taking higher doses faired better than those who did not.
The article stated this in their conclusions:
Ascorbic acid, zinc, vitamin D, and N-acetylcysteine have biologic plausibility for the prevention and treatment of COVID-19 and are candidates for clinical trials evaluating patients with these indications. Although there is likely little risk for patients taking labeled over-the-counter doses of these supplements, clinical evidence does not currently support routine use of any of these agents for the prevention or treatment of COVID-19. Unless a patient has a confirmed or suspected micronutrient deficiency, additional research is needed before providing doses of these agents higher than the recommended daily intake established by the US Department of Agriculture.