The conventional medication, Metformin ( also known as glucophage ) The biguanide class of antidiabetic medications, which also includes the withdrawn agents phenformin and buformin, originates from the French lilac or goat's rue (Galega officinalis), a plant used in folk medicine for several centuries.
It has been used for non insulin dependent diabetes for moire than 50 years. It has been used to treat PCOS ( polycystic Ovarian syndrome ) for a long time In the last 5 years metformin has been found to have anti cancer properties
New data now suggests that metformin can cause B12 deficiency. Metformin significantly increases the concentration of methylmalonic acid which is a cause of the neuropathy. This increase in methymalonic acid worsens the functional B12 staus of a patient.
This is a significant finding which must be addressed in all patients taking metformin. There are other ways to decrease high serum glucose levels in a diabetic as dietary and exercise lifestyle changes. The use of botanical herbs as bitter melon, fenugreek, rosemary and cinnamon can also decrease plasma glucose.